Nanomagnetic Relaxometry

Nanomagnetic relaxometry relies upon the ability to detect tiny magnetic particles by measuring the magnetic fields they release after they are magnetized, ie, when they “relax.”  Because low-frequency magnetic fields travel freely through human and animal tissue, we can measure these events both inside the body (in vivo) and in tissue samples (ex vivo).

Using specialized superparamagnetic nanoparticles that have biocompatible coatings and are linked to specific antibodies, we can determine whether these particles are bound to their specific targets using the large difference between the relaxation times of bound and unbound particles. The highly sensitive detectors we have developed allow us to measure, in vivo, the number of bound particles with unprecedented sensitivity, and to determine the location of these particles within 0.5 mm.

• Néel Decay and NP Optimization
• Néel vs Brownian
• SQUID Sensor
• Sensitivity